In Outlook, go to the Tools Menu and click on Email Accounts.
Select Add a new email account and then click Next.

Select POP3 and then click Next.

Enter your email information:
Your Name: your name
Email Address: the email address the messages will be sent from
Incoming Mail server (POP3): mail.domainname.xyz
Outgoing Mail server (SMTP): mail.domainname.xyz
User Name: the email address used to login to the webmail interface
Password: the password for the email address

Click on More Settings and Select the Outgoing Server Tab. Check My outgoing server (SMTP) requires authentication. Select Use same settings as my incoming mail server.

Click Ok. Click Next. Click Finish.
In Outlook Express, go to the Tools menu. Click on "Accounts..."

A box will appear. Click Add and select "Mail…"

Enter your name as you want it to appear on your emails and click Next.

Put in your email address, which consists of a user you set up in webmail and @yourdomain.xyz, and then click next.

Server type is POP3 and incoming and outgoing mail servers are mail.yourdomain.xyz (where yourdomain.xyz is your domain name and extension such as .com). Click on Next.

Next, enter your email address for the "Account name". Enter the password you set for this account. Note: Do NOT check the box "Log on using Secure Password Authentication".

Click Next and then click Finish. After you click Finish, you should see the following window. If not, go to the Tools menu, and click on "Accounts." After clicking "Accounts" the window will appear. In this window, click on your domain until it is highlighted, then click on "Properties."

8. When the next screen appears, click on the "Servers" tab. Under Outgoing Mail Server, check the box next to "My server requires authentication." Click Okay. Note: You MUST do this step so you can send mail from your domain.

Now, you're ready to send and receive mail. To set up multiple accounts, follow these steps again.